Ultrasound-Guided Transthoracic Mediastinal Biopsy: A Safe Technique for Tissue Diagnosis in Middle- and Low-Income Countries
Journal – cureus
Article type – Journal research article – Clinical research
Publication date – Mar – 2021
Authors – Muhammad Kashif Shazlee, Muhammad Ali, Muhammad Saad Ahmed, Junaid Iqbal, Jaideep Darira, Muhammad Qasim Naeem
Keywords – mediastinal biopsy associated mortality, mediastinal biopsy related complications, mediastinal mass, mediastinal tumours, ultrasound guided transthoracic mediastinal biopsy
Open access – Yes
Speciality – Cardiothoracic surgery, Other, Surgical oncology
World region Southern Asia
Language – English
Submitted to the One Surgery Index on March 26, 2021 at 5:32 am
Background and objectives
The high cost of video-assisted transthoracic procedures precludes their use in the diagnostics of mediastinal masses in low- and middle-income countries (LMICs). This study aims to assess the technical success rate and diagnostic yield of ultrasound-guided transthoracic mediastinal biopsies at a tertiary care hospital.
This descriptive cross-sectional study was conducted in patients presenting with mediastinal masses referred to radiology services at Dr. Ziauddin University Hospital. Karachi, Pakistan. Ultrasonography was performed using Toshiba Xario 200 & Aplio 500 using convex and linear probes accordingly. Biopsy was performed using a combination of 18G semiautomatic trucut and 17G co-axial needles. Complications and overall diagnostic yields were determined.
In all 70 patients referred, the procedure was completed successfully with an overall procedural yield of 95.7%. Inconclusive biopsies due to inadequate specimen were seen in two (4.2%) patients. No post-procedure major complication or mortality was observed. Minor complications were seen in three (4.2%) out of 70, including hematoma (<3 cm) in one patient and small pneumomediastinum in two patients.
Ultrasound-guided transthoracic mediastinal biopsy may be the pragmatic technique of choice in LMICs for the diagnosis of mediastinal masses as they provide real-time visualization and is cost-effective and safe
OSI Number – 20977