Diagnostic Accuracy of Core Needle Biopsy in Bone Tumors. Results of 100 Consecutive Cases from a Sarcoma Unit in Pakistan

Background: Histological diagnosis is the main step towards management of bone tumors. Although open biopsy is considered as gold standard but core needle biopsy is advantageous because of its low cost, low morbidity rates and less time consumption. The aim of this study was to determine the diagnostic yield of core needle biopsy.

Methods: From January 2016 to December 2018, 100 consecutive patients with suspected bone tumors underwent core needle biopsy in a single unit. Patients between 5 to 90 years of age were included in the study. Informed consent was obtained from all patients. Core needle biopsy was performed under Local or General anesthesia depending of the location of tumor and age. Multiple cores were obtained and were sent to a single histopathological lab.

Results: Out of 100 patients, 61 were male and 39 were females. The age range was from 5 to 73 years with a mean of 39 years. Diagnosis was made in 91% of cases with approximately 4% of them being negative and 5% of the patients had inconclusive results. Only 3 patients required repeat biopsy. None of our patients had any complications.

Conclusion: Core needle biopsy for diagnosis of bone tumors has high diagnostic and accuracy rates with minimal associated complications.