Second- and Third-Tier Therapies for Severe Traumatic Brain Injury

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Second- and Third-Tier Therapies for Severe Traumatic Brain Injury


JournalJournal of Clinical Medicine
Article typeJournal research article – Clinical research
Publication date – Aug – 2022
Authors – Charikleia S. Vrettou, Spyros D. Mentzelopoulos
Keywordsbrain trauma, intracranial hypertension, neuromonitoring
Open access – Yes
SpecialityNeurosurgery, Trauma surgery
World region Global

Language – English
Submitted to the One Surgery Index on September 2, 2022 at 8:55 am
Abstract:

Intracranial hypertension is a common finding in patients with severe traumatic brain injury. These patients need treatment in the intensive care unit, where intracranial pressure monitoring and, whenever possible, multimodal neuromonitoring can be applied. A three-tier approach is suggested in current recommendations, in which higher-tier therapies have more significant side effects. In this review, we explain the rationale for this approach, and analyze the benefits and risks of each therapeutic modality. Finally, we discuss, based on the most recent recommendations, how this approach can be adapted in low- and middle-income countries, where available resources are limited.

OSI Number – 21745

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