Journal – Annals of Medicine and Surgery
Article type – Journal research article – Clinical research
Publication date – Jul – 2022
Authors – Dereje Zewdu, Mekete Wondwosen, Temesgen Tantu, Tamiru Tilahun, Tewodros Teshome, Ahmed Hamu
Keywords – Acute appendicitis, Appendectomy, Perforated appendicitis, Postoperative complications
Open access – Yes
Speciality – General surgery
World region Central Africa, Eastern Africa, Middle Africa, Southern Africa, Western Africa

Language – English
Submitted to the One Surgery Index on July 28, 2022 at 12:41 am
Abstract:

Background
Previous studies have found an association between various predictors and perforated appendicitis. However, there is limited evidence of studies determining the severity of acute appendicitis (AA) in resource-limited settings. Thus, this study aimed to identify predictors and outcomes of perforated appendicitis (PA) in sub-Saharan countries.

Methods
This is a retrospective cohort study of 298 adult patients who underwent surgical intervention for acute appendicitis. Demographic characteristics, clinical parameters, intraoperative findings, length of hospital stay, and postoperative complications were collected. We computed multivariate logistic regression to identify predictors of PA. P-value 38 °C (AOR = 4.569; 95% CI (2.249–9.282), and duration of symptoms >2 days (AOR = 2.704; 95% CI (1.400–5.222). Perforation was associated with an increased rate of postoperative complications (45.07vs. 6.41%; P 38 °C were the best predictors of PA. The overall total postoperative complications and the length of hospital stays were higher in PA. Based on our findings, we recommend that the identified predictors should be considered during the preoperative diagnosis and subsequent management.

OSI Number – 21672

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