Journal – Scientific Reports
Article type – Journal research article – Clinical research
Publication date – Mar – 2022
Authors – My Hanh Bui, Quynh Long Khuong, Phuong Anh Le, The Anh Nguyen, Quoc Hung Doan, Tuan Duc Duong, Hoang Ha Pham, Thanh Viet Pham, Tien Hung Tran, Hong Ha Nguyen, Binh Giang Tran, Duc Hung Duong, Xuan Co Dao, Gia Du Hoang, Xuan Thanh Dao, Truong Son Nguyen, Quang Cuong Le
Keywords – burden of sepsis, health financial resources, medical care
Open access – Yes
Speciality – Critical care, Surgical infection
World region South-eastern Asia
Country: Vietnam
Language – English
Submitted to the One Surgery Index on March 31, 2022 at 2:12 am
Abstract:

Despite improvements in medical care, the burden of sepsis remains high. In this study, we evaluated the incremental cost associated with postoperative sepsis and the impact of postoperative sepsis on clinical outcomes among surgical patients in Vietnam. We used the national database that contained 1,241,893 surgical patients undergoing seven types of surgery. We controlled the balance between the groups of patients using propensity score matching method. Generalized gamma regression and logistic regression were utilized to estimate incremental cost, readmission, and reexamination associated with postoperative sepsis. The average incremental cost associated with postoperative sepsis was 724.1 USD (95% CI 553.7–891.7) for the 30 days after surgery, which is equivalent to 28.2% of the per capita GDP in Vietnam in 2018. The highest incremental cost was found in patients undergoing cardiothoracic surgery, at 2,897 USD (95% CI 530.7–5263.2). Postoperative sepsis increased patient odds of readmission (OR = 6.40; 95% CI 6.06–6.76), reexamination (OR = 1.67; 95% CI 1.58–1.76), and also associated with 4.9 days longer of hospital length of stay among surgical patients. Creating appropriate prevention strategies for postoperative sepsis is extremely important, not only to improve the quality of health care but also to save health financial resources each year.

OSI Number – 21545

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