The clinical efficacy of using autologous platelet-rich plasma in total hip arthroplasty: A retrospective comparative study

The clinical efficacy of using autologous platelet-rich plasma in total hip arthroplasty: A retrospective comparative study

JournalMedicine (Baltimore)
Publication date – Oct – 2018
Authors – Wang, X; Ma, J; Wang, Z; Xiao, L
KeywordsIntra-articular platelet-rich plasma; retrospective comparative study; total hip arthroplasty
Open access – Yes
SpecialityTrauma and orthopaedic surgery
World region Southern Asia
Country: China
Language – English
Submitted to the One Surgery Index on October 30, 2018 at 11:43 pm
Abstract:

This study evaluated whether intra-articular platelet-rich plasma (PRP) might prevent postoperative bleeding in total hip arthroplasty (THA).In this study, 260 hips that underwent THA were evaluated randomly by paramedical staffs, 130 of which involved the intraoperative use of PRP, and 130 of which served as control group. Postoperative blood loss (drain bag volume), estimated blood loss, and change in hemoglobin (Hb) at day 1, 2, 4, and 7 were analyzed, respectively.PRP-treated group had a significant decrease in mean postoperative blood loss (92.6 ± 168.2 mL) compared to control group (682.3 ± 185.5 mL, P < .01). The mean postoperative estimated blood loss (526.1 ± 236.1 mL) in the PRP-treated group was significantly less than that in the control group (629.2.2 ± 142.3 mL, P < .01). There was a statistically significant difference in Hb value (mg/dL) at day 1, 2, 4, and 7 (-1.35 vs -1.98, -1.59 vs -2.52, -1.96 vs -2.82, and -1.76 vs -2.47, P < .05).We found a significant reduction in postoperative blood loss (drain bag volume), estimated blood loss, and change in Hb after the use of autologous platelet gel in patients of THA, and PRP appears to be effective in reducing postoperative bleeding in THA.

OSI Number – 20267
PMID – 30290603

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